Anti-cardiolipin antibodies are auto-antibodies produced by the body that act against negatively charged cell membrane phospholipids of the heart muscle, platelets and endothelial cells. In this case, the body is often prone to hypercoagulability and thrombosis, i.e., a tendency to thrombosis. High titers of anti-cardiolipin antibodies are mainly seen in antiphospholipid antibody syndrome, where patients often have arteriovenous embolism and recurrent adverse pregnancy conditions. In addition, anti-cardiolipin antibodies are seen in many other diseases, such as: first, autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and scleroderma. Second, high anti-cardiolipin antibodies are also seen in viral infections, such as varicella virus, adenovirus, or mumps virus. Third, high anti-cardiolipin antibodies are seen in mycoplasma infections. Fourth, high anti-cardiolipin antibodies are also seen after the application of certain drugs, such as chlorpromazine. Fifth, high anti-cardiolipin antibodies can also be seen in 2% of normal people, especially in the elderly.”