Diabetes is a chronic disease, long-term diabetes blood glucose at a high level, will affect various organs of the body. First, the impact of large blood vessels. For example, the cardiovascular and cerebrovascular hazards can lead to coronary heart disease and cerebral infarction. Secondly, diabetes can affect the microvasculature and cause diabetic nephropathy and diabetic retinopathy. Third, diabetes can cause skin lesions, such as itching of the skin. Fourth, diabetes can affect the peripheral nerves and cause diabetic peripheral neuropathy.