Ankylosing spondylitis is still painful with Adamu, if it is just started, it is recommended to continue the treatment, which usually relieves within 12 weeks of treatment. If there is no relief after 12 weeks, it is recommended to consult a doctor. Ankylosing spondylitis is an autoimmune disease that is associated with a variety of causes, including genetics, environmental factors, and infections. The goals of treatment for ankylosing spondylitis are to eliminate or minimize symptoms, restore the patient’s physical function, and prevent complications. Adalimumab can be used to treat rheumatoid arthritis, ankylosing spondylitis, and other immune disorders, providing rapid relief of clinical symptoms in patients with ankylosing spondylitis. Data show that adalimumab usually works within 12 weeks of treatment, so after the initial use of adalimumab, ankylosing spondylitis will also appear pain, need to adhere to the use of pain will gradually reduce. If after 12 weeks of using adalimumab, the patient’s pain is still very strong, it is recommended to consult a doctor in time to adjust the treatment program. Ankylosing spondylitis is recommended to consult the rheumatology and immunology department in a timely manner, and must strictly follow the doctor’s instructions for the use of adalimumab, do not reduce or stop the drug without authorization, and follow up on a regular basis.