Physical stimulation of the oral mucosa during betel nut chewing and certain mutagenic components contained in betel nut chewables may cause oral fibrosis.
Long-term betel nut chewing can lead to atrophy of the oral epithelium, nail protrusion flat or disappeared, at the same time cause a large number of inflammatory cells infiltration of the oral mucosa lamina propria, resulting in the accumulation of local collagen fibers, disordered and vitreous, further development of the disease can be affected to the deeper layers of the muscle layer, resulting in the possibility of oral fibrosis.
Chewing betel nut caused by oral fibrosis of the specific etiology is not yet clear, but through the study shows that chewing betel nut can greatly increase the probability of suffering from oral fibrosis, it is recommended not to chew betel nut frequently on weekdays, reasonable with the diet, to avoid the adverse consequences of the discomfort in a timely manner for diagnosis and treatment.