In Chinese medicine, the disease is classified as “paralysis” or “bone paralysis”. Most of the cases are caused by old age, deficiency of qi and blood, and deficiency of liver and kidney, which leads to poor qi flow and internal obstruction of blood stasis, causing obstruction of meridians, loss of nourishment of tendons and bones, and pain when not honored. Zhang’s Medical General” cloud: “Knee is the house of tendons, knee pain is not due to liver and kidney deficiency, deficiency is attacked by wind, cold and moisture.” Therefore, if the kidney essence is sufficient, the bone marrow biochemical source, the bones are nourished by the bone marrow and strong, if the kidney essence is insufficient, the bone marrow biochemical lack of source, the bones are not nourished and the development of the disease. If the kidney is deficient, the lumbar organs are not nourished, so the waist and knees are sore and weak. It is also stated in “The Treatment of Paralysis” that “paralysis for a long time must have stasis of blood”. The deficiency can lead to blood stasis, and blood stasis aggravates kidney deficiency, and the two are interrelated and affect each other. The classical formula of the “Recipe for Kidney and Blood Stasis” (composition: Shu Di, Boneset, Eucommia, Cuscuta, Cortex, Fructus Lycii, Dou Wu, Cistanches, Angelica, Myrrh, Safflower), which is used to benefit the kidneys and resolve blood stasis, and to promote the flow of qi and circulation, has been widely used in the clinical treatment of osteoarthritis of the knee with very satisfactory results.