The duration of cotton biting in the mouth after tooth extraction needs to be analyzed on a case-by-case basis, which is directly related to the patient’s age, previous medical history (hypertension, diabetes, etc.), the presence or absence of infection in the tooth and the size of the extraction trauma. For healthy normal adults, the cotton ball needs to be bitten for 30-40 minutes after tooth extraction, and can be left without obvious active bleeding after the cotton ball is removed for 30-40 minutes; for elderly patients and patients with hypertensive disease, especially those who have taken aspirin drugs in the past, the time of biting the cotton ball in the mouth should be extended appropriately, and the blood seepage in the extraction wound can be checked at 40 minutes, and if there is no obvious If there is no obvious blood seepage, the cotton ball can no longer be bitten, and if there is obvious blood seepage, the cotton ball can be bitten again for 30 minutes and the blood seepage can be evaluated again; if the tooth extraction time is longer, more bone is removed or the incision is larger, the time of biting the cotton ball should be extended and evaluated for about 30 minutes, and suturing should be performed if necessary. In summary, the time of cotton bite after tooth extraction should follow the medical advice and recommendation of the attending physician to prevent prolonging the time of oozing and bleeding.