Many newborns develop jaundice, most of them are physiological, and some are pathological jaundice in newborns. Pathological jaundice in newborns should have the following characteristics: 1, jaundice appears too early, often within 24 h; 2, jaundice develops quickly and rapidly worsens to the whole body; 3, jaundice is heavy, not only the face, trunk, limbs are yellow, while the palms of the hands, soles are also yellow, the child’s skin is golden yellow; 4, jaundice delayed remission, that is, two weeks after term babies, four weeks after preterm babies still have not receded, or recede It reappears later. In order to detect pathological jaundice in a timely manner, it is important to observe the development of jaundice. If the baby is delivered in the hospital, do not forget to ask the doctor if the newborn has jaundice when you leave the hospital. It is also important to hold the child in natural light frequently after returning home to see if the skin is yellowing. There are many causes of pathological jaundice in newborns, such as hemolysis, infection, starvation, constipation, bleeding, etc., which require immediate medical attention. If treatment is delayed, it may cause bilirubin encephalopathy, which can result in lifelong disabilities such as mental retardation and cerebral palsy in children. Pathological jaundice in newborns has many causes, and the cause of the disease needs to be clarified during the examination. In addition to the routine use of light therapy and medication, some patients, such as those with maternal-infant blood group incompatibility or sepsis, need to be treated for the cause.