Untreated hepatitis B may further develop into cirrhosis or even liver cancer. Hepatitis B is a chronic disease of the liver caused by persistent HBV infection, which is mainly transmitted through blood or body fluids, mother-to-child transmission, and sexual contact. Hepatitis B has a 3% to 5% chance of progressing to cirrhosis every year, and cirrhotic patients are more likely to get liver cancer than the general population, so all these factors will affect the patient’s life expectancy, and the mortality rate is relatively high, so Hepatitis B has to be treated actively to avoid progressing to cirrhosis and liver cancer. Hepatitis B has a trilogy, chronic hepatitis B, cirrhosis and liver cancer, and patients with cirrhosis are more likely to get liver cancer than the general population. Therefore, patients suffering from hepatitis B should be actively treated so as not to progress into cirrhosis and even further develop into liver cancer. Hepatitis B can be prevented by hepatitis B vaccination in daily life.