Hands stained with chili pepper is very hot can be relieved by general treatment and medication to ease the discomfort, the treatment needs to be carried out under the guidance of a doctor. 1. General treatment: the main reason why hands are very hot after being touched by chili is that capsaicin in chili irritates the skin and causes pain. It is recommended to use a lot of water to rinse, avoid scratching, quit smoking and drinking, and avoid spicy and irritating food. 2. medication: when the symptoms are serious, you can apply local drugs such as mometasone furoate ointment to relieve discomfort, but also oral anti-allergy drugs such as cetirizine to improve the symptoms. Drugs are recommended to follow the doctor’s instructions, there are adverse reactions to the emergence of timely medical treatment, drug allergy is prohibited to use. After the hand stained chili pepper is very hot, it is recommended to actively cooperate with the doctor to receive standardized treatment to alleviate the symptoms.