The symptoms of pain in the bones of the whole body when sleeping at night may be caused by cold, overwork, cold, rheumatoid arthritis and rheumatoid arthritis and other rheumatic immune diseases, as follows: 1. 3, cold: such as patients suffering from viral cold, in the early stage of the cold may appear the symptoms of generalized pain, weakness; 4, rheumatoid arthritis, rheumatoid arthritis and other rheumatic immune diseases: pay attention to rest, avoid strain, available anti-inflammatory pain medication for symptomatic treatment. If the symptoms still cannot be relieved after the above treatment, further examination at the hospital is needed to clarify the cause and to provide targeted treatment according to the cause.