Insulin resistant patients taking metformin can usually stop taking the drug after insulin resistance improves, the time ranges from 3-6 months, or may be longer, should be decided under the guidance of the doctor according to the condition. Insulin resistance means that the body’s sensitivity to insulin decreases and more insulin is needed to lower blood sugar. Patients with insulin resistance who have not developed diabetes and are treated with active diet and exercise therapy, weight control, and metformin can usually stop taking the drug in 3-6 months after insulin resistance is restored, but it needs to be decided according to the condition. If the control is not good, then the patient may eventually develop diabetes, and need to take the drug for a long period of time. Patients with insulin resistance should use the medication under medical supervision.