Gallbladder wall thickening of 7mm, wall roughness, edema, and malignant lesions have a certain correlation, but does not directly cause malignant tissue, need to be combined with clinical symptoms and examination results of a comprehensive judgment. The corresponding changes in the gallbladder, first of all, consider the gallbladder inflammation, caused by the corresponding conditions, most of which are caused by the gallbladder bile excretion obstacles, and then infections will cause related manifestations. The gallbladder wall thickening, wall roughness, edema, if not actively treated for a long time, there is a certain possibility of malignant changes. However, it does not directly cause malignant lesions, but is a slowly progressive process. The corresponding changes in the gallbladder, accompanied by obvious abdominal pain, jaundice and other symptoms, you need to consult a doctor in time for observation, after diagnosis of the disease, under the guidance of clinicians for standardized treatment.