The common causes of plantar exfoliation are the following: 1, fungal infection of the foot: mostly unilateral onset, manifested as large erythema, accompanied by desquamation, can have blisters, vesicles, etc., more need to test the fungus can be diagnosed, the need for external use such as terbinafine hydrochloride ointment, compound nebivin ketoconazole cream, etc., if necessary, oral antifungal drug therapy; 2, eczema: mostly symmetrical onset, can also be manifested as erythema, papules, It can be treated with topical anti-inflammatory and anti-allergic creams such as mometasone furoate ointment, as well as topical Vaseline and other moisturizing drugs. During the disease, pay attention to less spicy hair, wear breathable shoes and socks, etc.; 3, palmoplantar pustulosis: manifesting as erythema, desquamation and pustules on the palms of hands and feet, a kind of pustular psoriasis, which needs to be treated after a clear diagnosis and can be treated with oral treatment such as Avia to regulate skin keratinization.