The antibodies produced by the tetanus vaccine usually last for about 10 years after the injection. The tetanus vaccine is mainly used to prevent tetanus bacillus infection, and the tetanus vaccine given as a child can also have the effect of preventing the occurrence of tetanus. For adults who have not received the tetanus vaccine, two tetanus shots in the first year and a booster shot in the second year can maintain the antibodies produced by the vaccine for about 10 years. During this period, if the patient has a relatively small wound, tetanus antitoxin vaccination is generally not necessary and the chance of tetanus is relatively low. If the wound is relatively large, especially if it is a contaminated wound, such as a rusty nail piercing the skin, the patient still needs prompt tetanus antibiotic inoculation. In addition, tetanus antitoxin can destroy the tetanus bacilli that enter the body, but it cannot produce antibodies, and patients need to be injected every time they have a large wound.