Water-soluble vitamins: vitamin B1, B2, B6, C, niacin, folic acid. Fat-soluble vitamins: vitamin A, vitamin D, vitamin E, vitamin K. Vitamin B1 Characteristics of action: involved in glucose metabolism and the function of the nervous and cardiac systems Deficiency manifestations: neurological reactions (dry pediculosis), cardiovascular system reactions (wet pediculosis), Wernicke’s encephalopathy, polyneuroinflammatory psychosis Adverse reactions: allergic reactions or shock may occur in large doses Adaptation: vitamin Adjunctive treatment for B1 deficiency-induced athlete’s foot, Wernicke’s encephalopathy, peripheral neuritis, dyspepsia, etc. Precautions: uric acid concentration should be measured in high doses, which is falsely elevated, and false-positive urinary cholagens may occur Interactions: deterioration and destruction with antacids, and degradation can be prevented by combining with calcium edetate Characteristics of action of Vitamin B2: Participation in the cellular redox system, transmission of the hydrogen reaction, and the promotion of fat, Sugar, protein metabolism Deficiency manifestations: pharyngolaryngitis, keratitis, lingual inflammation, labyrinthitis, facial seborrheic dermatitis, dermatitis of the trunk and limbs, anemia and neurological symptoms, corneal vasculature hyperplasia, cataract formation, scrotal inflammation, vaginitis Adverse effects: yellow urine after a large dose of the drug, occasional allergic reactions, rare hyperthyroidism Indications: Vitamin B2 deficiency due to stomatitis, dry and cracked lips and lingual inflammation, Scrotal inflammation, corneal vascularization, conjunctivitis, seborrheic dermatitis, etc. Precautions: can make the urine yellow Interactions: the application of phenothiazine antipsychotics, tricyclic antidepressants, probenecid, etc. can make the body’s demand for vitamin B2 increase, so that thyroxine, gastrointestinal stimulation drugs to reduce absorption. Vitamin B6 Characteristics: the human body can not lack coenzyme; involved in the normal metabolism of amino acids, carbohydrates and fats Deficiency: (1) skin: eyes, nose and mouth skin seborrheic skin damage; accompanied by lingual inflammation and stomatitis (2) the nervous system: peripheral neuritis; accompanied by swelling and tenderness of joints, especially the wrist joints Undesirable effects: long-term use of large quantities of severe neurological sensory abnormalities Adaptation evidence Prevention and treatment of vitamin B6 deficiency caused by drug poisoning; seborrheic dermatitis, dry and cracked lips; prevention and treatment of pregnancy and anti-tumor radiotherapy and chemotherapy-induced vomiting. Precautions: women in pregnancy ingesting large amounts of vitamin B6 can cause; newborns develop vitamin B6 dependence syndrome. Interactions: Isoniazid increases the excretion of vitamin B6 through the kidneys; causes anemia or peripheral neuritis; can increase the analgesic effect of non-steroidal anti-inflammatory drugs.