Bubbles on the gums may be the result of the presence of herpes, hand, foot, and mouth disease, aspergillosis, or a gum abscess. The diagnosis needs to be confirmed based on oral manifestations and laboratory tests. 1. Herpes. When the organism is infected with herpes virus, clusters of pinpoint-sized blisters can appear in any part of the oral mucosa, and the blisters can break down and erode, and viral particles can be found in tissue smears. 2. Hand, foot and mouth disease. Mostly seen in children, infected with coxsackie virus, can appear in the oral mucous membrane parts of the papule, can also be seen in the limbs. The virus can be isolated by throat swab blister fluid or fecal specimen. 3. Pemphigus. When suffering from autoimmune herpetic disease, blisters of different sizes can appear in the oral mucous membrane, blisters are easy to break, and can be pushed to move by hand. It occurs widely in the oral cavity. 4. Gingival abscess. When there is chronic periodontitis or periapical periodontitis, the inflammation can lead to the gum soft tissue area caused by gum abscess, the blisters contain yellowish-white pus, and need to be surgically incised and drained. Gums long bubble, it is recommended to go to the hospital in time to check the cause of targeted treatment.