The normal range of glomerular filtration rate (GFR) is 80~120ml/min. Glomerular filtration rate (GFR) reflects the filtration function of the glomerulus, and its normal value range is 80~120ml/min, but the size of the value has a certain correlation with age, gender and other factors, and relevant data show that when the human body after the age of 40 years, it will be reduced by 10 ml/min every 10 years. In general, the glomerular filtration rate is higher in men than in women; in addition, during pregnancy, there is a significant increase in the glomerular filtration rate, which gradually decreases to a normal level after delivery. Decreased glomerular filtration rate is mainly seen in acute and chronic renal insufficiency and other pathologic diseases, and can also be caused by hypothyroidism. The increase of glomerular filtration rate is mainly seen in the early stage of diabetic nephropathy and pathological diseases such as acromegaly. Patients with abnormal glomerular filtration rate are recommended to consult regular hospitals and receive standardized treatment under the guidance of physicians.