Diabetic nephropathy is a common complication of diabetes, according to the severity of diabetic nephropathy, diabetic nephropathy can be divided into 5 stages, the following gives you specific diabetic nephropathy stages: Stage I: characterized by increased glomerular rate filtration and increased kidney volume. This initial lesion is consistent with the level, but reversible, and can be restored after treatment, but not necessarily completely back to normal. This phase is typically characterized by a mild increase in kidney volume and an increase in glomerular filtration rate. The corresponding glomerular perfusion pressure intra-volume pressure is increased. However, the clinical symptoms are not very obvious in this stage, and generally the patients themselves cannot detect the abnormality, the glomerulus basically does not change, there is no protein urine discharge, and the renal function is normal. It can only be judged by laboratory tests. Stage II: The exclusion rate is normal in this stage but the glomerulus has shown structural changes. Patients will have transient proteinuria after strenuous exercise, which can return to normal after a little rest. Glomerular structure has been changed in this stage, with thickening of glomerular basement membrane and increase of glomerular thylakoid matrix. Patients in this stage still have no obvious abnormalities themselves and may often experience fatigue, but they recover quickly after a little rest, and this stage is still often ignored by patients. Stage III: Also called early stage. The exclusion rate is 20~200 mcg/min,the patient’s blood pressure is mildly elevated and glomerular wasting begins to occur. Diabetic nephropathy leads to increased blood pressure and increased urinary protein excretion, but if blood pressure is lowered at this stage, urinary protein excretion can be reduced. The patient’s basement membrane thickening and basement membrane thickening are more pronounced, the small glomerular arteries have become diseased, and some glomerular function has been lost. Patients develop mild edema. Stage IV: This stage is called clinical diabetic nephropathy or overt diabetic nephropathy. This stage is characterized by massive albuminuria, edema and hypertension. This stage is also known as overt diabetic nephropathy. This stage is characterized by the excretion of large amounts of proteinuria and the patient develops hypoproteinemia as well as severe generalized edema. This stage is characterized by massive destruction of glomeruli and is irreversible. Stage V: i.e. end-stage, patients in this stage appear. Once diabetic patients progress to this stage, due to extensive thickening of the glomerular basement membrane, the glomerular capillary lumen undergoes