Psoriasis is a chronic disease that is difficult to treat, and only part of psoriasis has the possibility of self-healing, the specific time varies from person to person, ranging from a few months to a few years. Psoriasis is a skin disease caused by a combination of factors, manifested as scaly red spots, plaques, etc. The disease is stubborn and prone to relapse, and it is difficult to be completely cured. Infection, drugs, trauma and other causes of mild psoriasis, in the removal of disease-causing factors, there is a possibility of self-healing, the specific course of the disease varies, as short as a few months, as long as a few years. The majority of psoriasis is difficult to cure by itself, but can be relieved by standardized treatment. Topical medications are the treatment of choice for most psoriasis, such as glucocorticoid preparations like hydrocortisone cream and dexamethasone cream, and calcium-modulated phosphatase inhibitors like tacrolimus and pimecrolimus. The specific treatment needs to be decided according to the condition, it is recommended to consult a doctor in time, follow the doctor’s instructions to standardize the treatment, the above drugs need to be used in accordance with the doctor’s instructions.