The use of progesterone to promote the early onset of menstruation, may produce the following hazards: 1, after the use of progesterone, patients may appear dizziness discomfort clinical symptoms, individual patients dizziness symptoms will be very obvious, affecting the normal life and work. Patients with mild dizziness can continue to take progesterone, and those with severe symptoms need to stop using the drug, or change the drug to use before bedtime. 2, patients may experience nausea and vomiting clinical symptoms after using progesterone. Progesterone has gastrointestinal stimulation symptoms, so after taking it, gastrointestinal dysfunction can occur. 3, progesterone is a progestin, after using it, there may be breast swelling and discomfort, especially in patients with breast hyperplasia, breast discomfort will be more pronounced after the use of it. 4, may lead to menstrual disorders, women’s menstruation in the ovary cyclic hormone level changes in the normal cycle, the use of progesterone disrupts the normal hormones, easily lead to menstruation. 5, the use of progesterone may cause menstrual disorders, but it is not necessary to stop using progesterone. The use of progesterone disrupts the normal hormones and can easily lead to irregular menstruation.