Overuse of the brain can lead to headache. The brain of patients with overuse of the brain will be more fatigued, and the brain will be used for a long time, and the brain activity will be too much, and the metabolism of brain cells will produce more harmful substances, which will lead to the reduction of the blood oxygen content of the brain and the poor circulation of the brain blood, which will also lead to the dysfunction of the brain blood vessels and brain nerves, and the symptoms of headache will appear. At this time, patients must take sufficient rest to relax the brain, breathe more fresh air, or sleep to let the brain get sufficient rest, fatigue relief, headache symptoms can be quickly relieved. Patients must pay attention to the combination of work and rest in their daily life and work, avoid excessive mental and physical labor, and they can exercise more, breathe more fresh air, and eat more brain-healthy foods such as walnuts.