Discolored spots on the face may be caused by chloasma, freckles, nevus of Ota, etc. They can be eliminated by topical medication, systemic medication, laser treatment and so on. 1. Topical drug treatment: using decolorizing agents such as 2%~5% hydroquinone cream, 4% tretinoin, 15%~20% azelaic acid cream, compound arbutin cream can inhibit the activity of tyrosinase and reduce the production of pigment, etc. 0.025%~0.1% retinoic acid ointment can also affect the metabolism of melanin, which is of certain curative effect. 2. Systemic medication: Oral antioxidant medication such as vitamin C, vitamin E and tranexamic acid can reduce melanin production by inhibiting and removing oxygen free radicals to eliminate pigmentation. 3. Laser treatment: such as Q-switch, ruby laser, alexandrite laser, etc., which can remove local pigment particles and achieve the purpose of eliminating pigmentation. It is recommended that patients who want to eliminate pigmentation spots should go to the hospital for consultation and choose the appropriate treatment method under the guidance of doctors, and do not use drugs by themselves to avoid adverse reactions.