Long-term low potassium or potassium deficiency can not take valsartan hydrochlorothiazide tablets. Valsartan hydrochlorothiazide tablets can increase the excretion of potassium, long-term low potassium or potassium deficiency patients take, will cause further deficiency of potassium ions in the body, can cause a series of symptoms such as cardiac arrhythmia, muscle spasm, etc., so long-term low potassium or potassium deficiency patients can not take the drug. There are many reasons for long-term low potassium or potassium deficiency, such as long-term use of potassium-excreting diuretics, aldosteronism, etc. Patients should go to the hospital for standardized diagnosis and treatment in order to avoid delaying the condition. Valsartan hydrochlorothiazide tablets are mainly composed of valsartan and hydrochlorothiazide. Among them, valsartan is a specific angiotensin II receptor antagonist, which can inhibit the blood pressure-raising effect of angiotensin II; hydrochlorothiazide acts on the proximal end of the distal convoluted tubule to increase the excretion of sodium, chloride and potassium and reduce plasma volume. The drug treats mild or moderate essential hypertension that is not adequately controlled by a single drug. Adverse effects such as headache, dizziness, fatigue, cough, pharyngitis, nausea, diarrhea, dyspepsia, dysuria, frequent urination, arthritis, myalgia, visual disturbances, and conjunctivitis may be associated with the use of the drug. When combined with potassium-preserving diuretics, potassium-supplementing drugs, and drugs with potassium-enhancing benefits such as heparin, blood potassium concentrations need to be monitored. It is contraindicated in the following conditions: hypersensitivity to the drug or sulfonamide derivatives; pregnant women; severe hepatic failure, biliary depletion or biliary cirrhosis; creatinine clearance <30 ml/min or anuria; refractory hypokalemia, hyponatremia; hypercalcemia and symptomatic hyperuricemia. If you need to use the drug patients, please be sure to strictly comply with the doctor’s instructions under the guidance of the medication, do not self-medication.