Digestive system diseases are a group of frequent and common diseases, using a variety of drugs, and due to the needs of the disease, there are many special uses and precautions for oral drugs. In order to enable patients to achieve better therapeutic effects and reduce toxic side effects, the following drugs should be taken at the following times: 1. Drugs to be taken before meals (30-60 minutes before meals): aluminum thioglycollate, domperidone, montelukast, etc.; Ma Xiangtao, Department of Pediatrics, Anyang Third People’s Hospital 2. Drugs to be taken before or during meals: pepsin, pancreatic enzymes, etc.; 3. 3. Drugs to be taken after meals (15 to 60 minutes after meals): Bifidobacterium triptans, Bifidobacterium quadruplex tablets, if these two drugs are combined with antibacterial drugs, an interval of 2 hours is required, usually antibacterial drugs are taken first or as prescribed by the doctor. 4. Drugs to be taken on an empty stomach: omeprazole enteric-coated tablets.