Total excision of breast cancer usually does not preserve the nipple, some farther from the tumor may preserve the nipple. Breast is composed of skin, fibrous tissue, mammary glands and fat. Breast cancer is a malignant tumor formed by uncontrolled proliferation of mammary epithelial tissues under the action of multiple carcinogenic factors. Once diagnosed with breast cancer, total excision of breast cancer is a common treatment for breast cancer, which is suitable for early radical treatment of breast cancer. The entire breast, including the nipple, must be removed. However, it may be possible to preserve the nipple if it is located farther away from the tumor. After surgery, the need for follow-up radiation and chemotherapy will be determined based on pathological staging. After total mastectomy for breast cancer, patients should take effective care of the surgical wound to avoid infection, and should follow the doctor’s instructions for regular checkups during and after treatment.