Itchy face and body at night when sleeping may be physiological factors, such as dry skin, etc.; may also be pathological factors, such as eczema, contact dermatitis and other diseases. 1. Physiological factors: common such as dry skin, sleep at night indoor temperature is too high, humidity is too low will lead to increased loss of skin moisture. At this time, the skin is easy to become dry, the patient will appear itchy skin, skin peeling and other manifestations. This is a normal physiological phenomenon, generally pay attention to skin cleaning and moisturizing, sleep at night on the face and body itching symptoms will improve. 2. Pathological factors: (1) eczema: the cause of eczema is not clear, considerations related to heredity, abnormal immune function, hormonal changes in the body and other factors. Patients will appear red spots, papules, flaking, itching and other manifestations, if the patient’s face and body eczema, in the night time when sleeping on the face and body itchy symptoms. (2) Contact dermatitis: contact dermatitis may be caused by the bedding detergent is not clean, sleep at night contact bedding sensitizing detergent. Patients may show papules, erythema, blisters, itching, and so on, so patients will sleep at night with the manifestation of itchy face and body. (3) Other: patients with insect bite dermatitis, psoriasis, helminthic mite disease, urticaria, etc. can also cause itchy face and body when sleeping at night. If the dry skin causes itchy face and body at night, it can be left untreated, and the symptoms will usually improve after paying attention to skin moisturizing. If the itchy skin is caused by a disease, you need to consult a doctor, who will choose the appropriate measures for the cause of the treatment.