Methylcobalamin adherence to the consequences of taking a year is mainly related to the patient’s condition, peripheral neuropathy condition can be achieved cure, remission and ineffective, but also the adverse effects of the drug including rash, loss of appetite, diarrhea and so on. Methylcobalamin is mainly used for the treatment of peripheral neuropathy, after using the drug can achieve cure or remission, and some patients with ineffective treatment. Some patients may experience adverse reactions, such as allergic reactions, including skin rash, itching and other symptoms, and may also experience gastrointestinal symptoms, such as loss of appetite, nausea, vomiting, diarrhea and so on. The medication should be noted that if the drug is ineffective for more than one month, there is no need to continue to take the drug; long-term staff engaged in mercury and compounds can not be used in large quantities for a long period of time; the product should be kept away from light and moisture after opening, and is prohibited for patients who are allergic to methylcobalamin. It is recommended that the patient under the guidance of a doctor to use medication, do not blindly take medication, so as not to delay the condition.