Advanced vulvar cancer spreading can lead to rectal and urethral symptoms, inguinal lymph node metastasis or corresponding symptoms caused by metastasis of other organs. Most of vulvar cancer is squamous cancer, and the tumor is easy to be broken and infected, etc. Late-stage vulvar cancer is mostly manifested as local ulceration, pain and swelling. After tumor enlargement and ulceration, it will cause urinary tract symptoms, such as frequent urination, painful urination, difficulty in urination, etc. If it presses the rectum, it can cause difficulty in defecation. Tumor can also metastasize to inguinal lymph nodes and cause inguinal lymphatic enlargement, which can be felt locally, and if the lump becomes bigger, it can also cause lower limb edema. In advanced stage, vulvar cancer can also metastasize to other organs and cause corresponding symptoms, for example, metastasis to liver will cause right side abdominal pain or even jaundice. Patients who are diagnosed with vulvar cancer should actively cooperate with the treatment to improve the prognosis.