Isotretinoin can be combined with anti-inflammatory medications such as amoxicillin capsules and levofloxacin. Isotretinoin medications are available in capsules as well as topical gels. This type of medication is mainly used to treat skin conditions such as acne. It reduces sebum production, shrinks hair follicles and reduces keratinization of the cortical layer. However, it is contraindicated for those who are allergic to the product. If acne is severe, with pustules and localized redness, it can be used with amoxicillin capsules, which belong to the broad-spectrum penicillin group of antibiotics. The drug can be used to treat infections of the respiratory tract, skin tissues, and urinary tract. However, people with penicillin allergy should not use the drug. People with penicillin allergy can use levofloxacin tablets. Levofloxacin tablets belong to the fluoroquinolone antibiotic group. It can be used to treat infections caused by sensitive genera of bacteria, with adverse reactions such as tendon rupture and diarrhea. It is contraindicated for those who are allergic to this product. Please use the medicine under the guidance of a physician.