Clinically, it is impossible to determine what kind of disease is suffered by a positive urine ketone body alone, and many conditions can appear positive urine ketone body. Urine ketone body test is mainly used in clinical judgment and evaluation of impaired glucose metabolism and incomplete fat oxidation, and the following conditions can commonly appear positive urine ketone body: 1, drug factors: diabetic patients taking oral metformin hypoglycemic drugs, because hypoglycemic drugs can inhibit cellular respiration and affect the body’s fat oxidation metabolism, the patient’s test report may indicate positive urine ketone body; 2, diabetic ketoacidosis. Patients with diabetic ketoacidosis, due to reduced glucose utilization, the ketone body produced by the body’s breakdown of fat will increase, resulting in positive urine ketone bodies. It is often used clinically for differential diagnosis with acidosis or coma caused by other diseases; 3. Infectious diseases: Patients suffering from infectious diseases may also show positive urinary ketone bodies, such as pneumonia, acute upper respiratory tract infection, sepsis, tuberculosis, etc.; 4. Inadequate body intake: When the body has severe diarrhea and vomiting, malnutrition may occur, and also if there is prolonged starvation, due to excessive fat metabolism. 5, the body absorption disorders: such as suffering from gastrointestinal tract diseases or liver diseases, resulting in malabsorption, while the synthesis and storage of glycogen function of the liver decreases, and when the sugar metabolism is impaired, it will break down fat to produce energy, thus making the urinary ketone body positive; 6, other: if the patient is in chloroform, ether anesthesia, or phosphorus poisoning, etc. If the patient is under chloroform, ether anesthesia, or phosphorus poisoning, as well as after strenuous exercise, urine test results may also indicate positive urine ketone bodies.