Colchicine side effects are not significant when taken in small doses. A common side effect of colchicine is diarrhea, which should be discontinued immediately if this occurs. The usual routine dose is one tablet in the morning and one tablet in the evening. If you have diarrhea in the morning and one tablet in the evening, you can reduce the dose to one tablet once a day. If one tablet a day still causes diarrhea, the drug needs to be stopped and other anti-inflammatory drugs for gouty flare-ups should be chosen under the guidance of a doctor. Colchicine can not be used as a long-term therapeutic drug, otherwise it will lead to a lot of serious adverse reactions, so be careful, you can take painkillers, diclofenac sodium or colchicine in the acute stage, but it is only temporary pain relief, not effective treatment. The use of medication should be under the guidance of a physician, do not take without authorization.