Born with an inability to rotate the eyeballs is usually caused by diseases of the oculomotor, trochlear and abducens nerves, hypoplasia of the extraocular muscles, paralysis of the ocular muscles, and so on. 1. Diseases of the motor, gliding and abducens nerves: Diseases of the motor, gliding and abducens nerves may be caused by cerebral arteriosclerosis, aneurysms, etc. Patients may have double vision, downward strabismus, etc., which may also lead to the patient’s eye movement disorders and inability to rotate freely. 2. Extraocular muscle hypoplasia: Patients with extraocular muscle hypoplasia, which is usually caused by differentiation defects in the developing mesoderm, may have symptoms such as ptosis and eye movement disorders. 3. Oculomotor palsy: Oculomotor palsy may also lead to ocular motility disorders, in which patients are born with eyes that do not rotate. It is usually caused by hydrocephalus and brainstem stroke, and patients may also have symptoms such as eye deviation and pupil dilatation. It is recommended that patients with ocular motility disorders seek medical attention in a timely manner to have their condition evaluated and treated under a doctor’s supervision.