In general, hepatitis B cannot be cured by taking royal jelly for five years. Hepatitis B is triggered by hepatitis B virus, and royal jelly is secreted by the pharyngeal head glands of young worker bees that cultivate larvae, which has high nutritional value and contains many nutrients such as folic acid, inositol, and acetylcholine, etc. Although it can provide more nutrients for the human body’s life activities, royal jelly can not eliminate the hepatitis B virus, so it is not possible for the patients to be cured of hepatitis B by eating royal jelly. The treatment of hepatitis B needs to be individualized and comprehensive, and patients need to carry out basic treatment through sufficient rest, reasonable diet, adjusting the mind, and reducing liver damage. For those who need to give antiviral treatment, comprehensive assessment of the patient’s condition is also needed to formulate a detailed antiviral program. For those with end-stage cirrhosis and liver failure, liver transplantation can be considered. Hepatitis B has the risk of developing into cirrhosis and liver cancer, and dietary supplements cannot replace medication, so patients should cooperate with doctors for treatment as early as possible.