The process of PICC extubation is divided into the steps of preparation before extubation, local disinfection, and extubation, as follows: 1, preparation before extubation: first of all, an ultrasound must be done, and it is a vascular ultrasound to confirm that there is no thrombus around the PICC tube; 2, local disinfection: the skin around the tube must be disinfected for 15 cm, and local flushing is also required to confirm that the PICC tube is not blocked. No blockage, and then to remove part of the suture, especially to remove the suture of the fixed tube; 3, extraction: must be removed after the tube to confirm that there is no fracture, no partial defect, and then local gauze pressure for 1-2 minutes to observe no obvious bleeding, after local gauze coverage, and then fixed with adhesive tape, then basically completed the operation of PICC extraction.