Systolic blood pressure is high and diastolic blood pressure is not high, which is clinically known as simple systolic hypertension, and can be treated with drugs, mainly calcium antagonists and other drugs. Elevated systolic blood pressure and low diastolic blood pressure are usually caused by poor arterial elasticity, which is common in the elderly. Oral calcium antagonists, such as amlodipine and nifedipine controlled-release tablets, angiotensin-converting enzyme inhibitor ramipril, and angiotensin receptor antagonist temsirolimus can be taken orally. Oral diuretics hydrochlorothiazide can also be taken. These commonly used antihypertensive drugs if single use can not control blood pressure to meet the standard, can be 2 ~ 3 antihypertensive drugs used in combination. In the process of using the drugs, strictly follow the time and number of doses, pay attention to the occurrence of adverse reactions such as edema, palpitations, flushing, dry cough, and so on. Timely adjustment of drugs. It is recommended that hypertension medication regular to the cardiology department, by the professional doctor to guide the treatment.