There are no new drugs for the treatment of vitiligo, and commonly used drugs include hormones such as halometasone ointment, topical calcineurin inhibitors such as tacrolimus ointment, and topical vitamin D3 derivatives such as topical capotriol ointment. 1. Hormone therapy: (1) local topical hormone: white spots involved in the area <3% of the body surface area of the progressive lesions, you can choose a strong hormone such as halometasone ointment, etc., can be very good inhibition of the disease progression, if the continuous use of 3 to 4 months without recoloration, that is, the efficacy of the treatment is poor, need to be replaced or combined with other local therapeutic options. (2) systematic use of hormones: progressive vitiligo can be early oral hormones, such as oral prednisone, intramuscular injection of compound betamethasone injection. 2. topical calcineurin inhibitors: mainly pimecrolimus ointment and tacrolimus ointment, especially for the face, armpits and other thin and tender skin. 3. Topical vitamin D3 derivatives: such as topical captopanol ointment or tacalcitol ointment, can also be used in conjunction with topical hormones and calmodulin inhibitors. If you have been diagnosed with vitiligo, you need to go to the hospital in a timely manner and be treated by a doctor in a standardized manner to avoid delays. Drugs need to be used in accordance with medical advice.