There are two clinical indicators of blood calcium concentration, one is the normal value of total serum calcium, between 2.25-2.65 mmol/L. The other is the normal value of serum ionized calcium, which is between 1.0-1.2 mmol/L. The other is the normal value of serum ionized calcium, which is between 1.0-1.2 mmol/L. Calling blood calcium above 2.75 as hypercalcemia, the clinical manifestations of hypercalcemia are mainly due to neurological manifestations, such as patients may experience memory loss, decreased calculation, depression, indifference and drowsiness. Hypercalcemia decreases neuromuscular excitability, leading to muscle weakness and even difficulty walking and weakened tendon reflexes. It can also manifest as hypertension, shortened QT interval, bradycardia, and increased sensitivity to digitalis drug sensitivity. For patients with hypocalcemia, calcium sodium below 2.15 mmol/L is called hypocalcemia. The most common clinical manifestations of hypocalcemia are numbness in the mouth, lips, between the fingers or feet, ankylosis, and spasm of the smooth muscle of the pumping animals.