Myocardial fibrosis is mainly treated by surgery, drug treatment has some effect, but the effect is limited. 1. Surgical treatment: commonly used surgical methods include endocardiectomy, atrioventricular valve repair or replacement, heart transplantation and so on. (1) Endocardiectomy: it is suitable for patients with normal ventricles but limited diastolic function, aiming at removing endocardial fibrous hyperplasia and calcification. (2) Atrioventricular valve repair or replacement: For severely damaged valves, the purpose is to repair or replace fibrotic lesions, which can restore the normal function of the valve. (3) Heart transplantation: applicable to patients without severe pulmonary hypertension, the purpose is to prolong life and improve the quality of life of patients. 2. Drug therapy: commonly used drugs include glucocorticoids, diuretics, β-blockers, anticoagulants and so on. (1) Diuretics: such as spironolactone, furosemide, etc., to reduce the burden on the heart by promoting the excretion of urine. (2) Beta-blockers: e.g. metoprolol, etc. are used to protect heart muscle cells and improve symptoms. (3) Anticoagulants: e.g., warfarin, etc., to prevent blood clots from forming. If myocardial fibrosis is diagnosed, it is recommended to consult a doctor in time and actively cooperate with the treatment.