Itching down there in girls is usually caused by vaginal inflammation, commonly bacterial vaginitis, vulvovaginal pseudomonal yeast disease, and trichomoniasis. If a patient has itchy bottom, she should wash her vulva with water, not wear tight clothes and chemical fiber pants, and change her underwear and underwear regularly. If the symptoms are significantly relieved after the above treatment, further treatment is not needed. If the symptoms are still present after the above treatment, it is recommended to consider topical application of topical dampness and anti-itch ointment and nifurtimox vaginal ointment. If symptoms are still present after topical treatment, further laboratory tests of vaginal secretions are needed to determine the next step of treatment based on the vaginal secretions examination.