Lower extremity venous embolism anticoagulants include heparin, direct factor Xa inhibitors and other drugs. Suffering from this disease, the use of related drugs should be carried out under the guidance of a doctor, and surgical treatment is needed for serious cases. 1. Heparin: it is an anticoagulant, which has anticoagulant effect both in vivo and in vitro, and can be used for the prevention and treatment of thrombosis-related diseases. Its effects are anticoagulation, inhibition of platelet adhesion and aggregation, and inhibition of excessive system activation. Allergy to heparin, pregnant women, patients with bleeding tendency are prohibited. 2. Direct factor Xa inhibitor: Rivaroxaban is often used, which can highly selectively and competitively inhibit free and bound factor Xa and thromboplastin activity to achieve the purpose of anticoagulation. It is contraindicated in patients with allergies, pregnant women, chronic ulcers, bleeding tendencies, and severe hypertension. The drugs that can also be used are low molecular heparin, warfarin, argatroban, etc. In the event of lower extremity venous embolism, you should go to the hospital in time for diagnosis and treatment, and actively treat it, and do not believe in the biased prescriptions and tests, so as not to cause danger.