Oligodendroglioma grade 2 refers to oligodendroglioma grade 2, a disease that is difficult to cure but can be treated with surgery, radiation therapy, and chemotherapy to relieve symptoms and maintain stability. Oligodendrocytomas are neuroepithelial tumors derived from oligodendrocytes. Generally, timely surgical treatment, radiotherapy and chemotherapy for oligodendroglioma can effectively alleviate the clinical symptoms, improve the quality of life of patients and maintain the stability of the disease, however, most oligodendroglioma grade 2 cannot be cured. The prognosis of this disease is related to the severity of the disease, treatment effect and patient compliance and other factors. Moreover, oligodendrocytes are low-grade malignant tumors and usually have a good prognosis, with a median survival period of about 7 to 10 years, a 5-year survival rate of about 65.3%, and a 10-year survival rate of about 47%. In summary, when patients are diagnosed with oligodendroglioma grade 2, they should standardize the treatment under the guidance of doctors, strengthen the daily life management, and follow up regularly.