Slightly coarse liver echo is a common term used in liver ultrasound to mean that there is damage to the liver, which is commonly seen in fatty liver, hepatitis, and liver fibrosis. There is no specificity of slightly thick liver echo in women, which is the same as the reason why liver echo is slightly thick in general people. 1. Fatty liver: a lot of fat has accumulated in the liver cells, leading to diffuse steatosis of the liver cells, and at this time, the echo of the liver will be coarsened by ultrasonography. 2. Hepatitis: such as viral hepatitis, alcoholic hepatitis, drug hepatitis, which often leads to necrosis of liver cells, resulting in thickening of liver echoes. 3. Liver fibrosis: chronic liver disease, liver cells will be repeatedly destroyed and repaired, ultrasound will appear liver echoes slightly thicker performance. Other diseases that cause impaired liver function, such as hepatobiliary system diseases, biliary system obstruction or infection, adverse reaction of chemotherapy drugs, etc., may lead to coarsening of liver echoes. It is recommended to improve the examination to clarify the cause of the disease, and give targeted treatment or therapy under the guidance of the doctor.