Generally Tadalafil taking 40mg is prone to serious adverse reactions, which are characterized by chest pain, hearing loss, allergies, and nasal bleeding. Tadalafil is mainly used to treat erectile dysfunction. In most cases, the dosage of this product should not exceed 20mg, tadalafil taking 40mg is an overdose of the drug, which is prone to serious adverse reactions, which can be manifested as chest pain, tachycardia, hearing loss and so on. In addition, there may be skin itching, red rash, shortness of breath and other signs of drug allergy, or nasal congestion, muscle pain, flushing and other manifestations. In this case, it is necessary to stop the drug immediately and go to the hospital. In summary, patients must take tadalafil under the guidance of a doctor, do not self-medicate or increase or decrease the dosage of medication, to prevent adverse effects on health, delay treatment and aggravate the original disease.