Women with weak and achy calves need to be alert to diseases such as osteoporosis and anemia, which may also be related to other diseases such as low blood pressure and hypokalemia. 1. Osteoporosis: the loss of matrix in the bones due to diseases, medications, decreased hormone levels, etc., thus causing osteoporosis, a systemic bone disease, increased brittleness within the bones, which will lead to the symptoms of soreness and weakness of the calves. 2. Anemia: due to the decrease or insufficiency of red blood cell production, resulting in a decrease in the ability of blood to carry oxygen, causing insufficient oxygen supply, the calf is in a state of oxygen deficiency for a long period of time, and the symptoms of soreness and weakness will occur. 3. Other diseases: mainly low blood pressure and hypokalemia, lower blood pressure in the body or lack of potassium in the blood, it is easy to appear the symptoms of weak and achy calves. After the occurrence of calf weakness, it is recommended to go to the hospital in time for relevant examinations to clarify the causes of calf weakness, so as to avoid delaying the condition and affecting the health of the body.