There are many causes of atrophy of one leg, such as damage to the peripheral nerves of the leg, prolonged lesions can lead to atrophy of the muscles of one leg, in addition to diseases and diseases of the muscular nerve junction, ionic disorders can lead to atrophy of one leg. Central lesions such as acute cerebrovascular disease, where the patient develops hemiplegia or paralysis of one leg, and long-term disuse can lead to the development of disuse atrophy. There are many causes of leg atrophy. It is recommended that patients undergo nuclear magnetic examination of the lumbar spine and head to exclude degenerative and disuse leg muscle atrophy caused by cerebrovascular disease leading to hemiparesis, and also to exclude leg atrophy caused by peripheral nerve damage due to compression of the nerve roots by the lumbar intervertebral disc, and peripheral nerve damage causing atrophy of one leg.