The treatment of chronic chemoattractive atrophic gastritis with sinus erosion includes general treatment, causative treatment and symptomatic treatment. Commonly used drugs include omeprazole, domperidone, amoxicillin, colloidal bismuth pectin, etc. 1. General treatment: regular and light diet is recommended, avoiding stimulating food; such as emotional stability, avoiding anxiety and depression; such as moderate exercise, avoiding prolonged sitting and lying down. 2. Allopathic treatment: If there is Helicobacter pylori infection, proton pump inhibitors (e.g., omeprazole, pantoprazole), antibiotics (e.g., amoxicillin, clarithromycin), bismuth (e.g., bismuth colloidal bismuth, bismuth potassium citrate) and other drugs can be given. 3. Symptomatic treatment: if acid reflux, heartburn can be given proton pump inhibitors; if nausea, vomiting can be given domperidone, mosapride and other drugs; such as belching, loss of appetite can be given to the compound digestive enzymes, mitochondrial pancreatic enzyme tablets and other drugs. For the treatment of chronic saprophytic atrophic gastritis with gastric sinus erosion, it is recommended to consult a doctor in time and follow the doctor’s instructions.