Total cholesterol of 5.25 mmol/L is borderline elevated and requires high attention. The normal value of total cholesterol is <5.18mmol/L, 5.18-6.19mmol/L is borderline elevated, and ≥6.22mmol/L is elevated. So total cholesterol of 5.25mmol/L is borderline elevated. However, the reference value of each instrument is not exactly the same, so it is necessary to check the reference value of the combined instrument for specific judgment. Cholesterol is the raw material for the synthesis of sex hormones, bile acids, vitamin D and other substances, and is also involved in the synthesis of cell membranes. Total cholesterol is the sum of free cholesterol and cholesteryl esters. Elevated cholesterol is prone to co-occur with hypertension, coronary heart disease and other diseases, so it needs to be controlled in time. It is recommended to have moderate activity, maintain good rest and dietary habits, avoid eating high cholesterol foods such as egg yolks and animal offal, and monitor cholesterol levels. If total cholesterol is elevated, you should seek medical attention.