Statins may cause elevated blood sugar. Statins are a class of lipid-regulating, plaque-stabilizing drugs that are more widely used in clinical practice, and common statins include atorvastatin and resuvastatin. Statins are selective, competitive inhibitors of hydroxymethylglutaryl coenzyme A reductase, and there are reports showing that the use of hydroxymethylglutaryl coenzyme A reductase inhibitors is associated with increased levels of glycosylated hemoglobin and fasting glucose. Patients who need long-term treatment with statins should take the medication under the guidance of a professional doctor and go to the hospital regularly to monitor the efficacy of the medication and the adverse effects, and adjust the treatment program in time.