Renal collecting duct carcinoma and renal medullary carcinoma: renal collecting duct carcinoma is a malignant epithelial tumor originating from the collecting duct of Bellini; renal medullary carcinoma originates from the collecting duct in the proximal cortical area, and patients almost always have sickle cell hematopathy. The two have some similarities in terms of gross and histological manifestations and are described together.
- Gross examination: Both occur in the central part of the kidney, in the medulla, with solid, gray-white, indistinct borders and visible necrosis.
- Histopathology: It should be noted that Bellini’s collecting duct carcinoma is often a diagnosis of exclusion, and the site of the tumor is important in making the diagnosis, with histologically irregular tubular structures and highly heterogeneous cells.