The left side of the navel is painful when pressed, and the specific treatment plan needs to be determined in conjunction with the cause of the disease. Common causes include intestinal inflammation, mesenteric sebaceous membrane inflammation, peritonitis, and skin boils, etc. Treatment options include medication, surgery, and daily care. 1. Intestinal inflammation: Bacterial enteritis can cause localized pressure pain and can be treated with drugs such as levofloxacin; ulcerative colitis can also cause pressure pain and can be treated with salicylic acid drugs, such as mesalazine, etc., which can be combined with hormonal drugs, such as hydrocortisone. 2. Mesenteric lipomatosis: the disease is to abdominal pain as the main manifestation of mesenteric disease, clinically rare, the pathological manifestation of non-specific inflammation caused by extensive thickening of the mesentery followed by fibrosis. Glucocorticosteroids (e.g. prednisone) and immunosuppressive drugs (e.g. hydroxychloroquine, azathioprine, cyclophosphamide, etc.) are needed. 3. Peritonitis: Infection, perforation and other causes of peritoneal inflammation, resulting in localized irritation can also cause symptoms of pressure pain. Intravenous ceftriaxone sodium, levofloxacin and other broad-spectrum antibiotics should be used, and if necessary, surgery should be performed. 4. Skin boils: skin boils can be treated with topical mupirocin ointment. The left side of the navel is painful when pressed, it may also be caused by abdominal visceral lesions, we should consult a doctor in time, improve the examination, clear diagnosis and standardized treatment in accordance with the doctor’s instructions, to avoid delays in the condition.